Selected publications in 2014

Cascleave 2.0, a new approach for predicting caspase and granzyme cleavage targets.
Wang M,Zhao XM, Tan H, Akutsu T, Whisstock J, and Song J.
Bioinformatics (2014)

We develop a new bioinformatics tool, termed Cascleave 2.0, which builds on previous success of the Cascleave tool for predicting generic caspase cleavage sites.

Comments on "Human Dominant Disease Genes Are Enriched in Paralogs Originating from Whole Genome Duplication".
Chen WH, Zhao XM, Noort V and Bork P.
PLoS Computational Biology (2014)

This Formal Comment is a response to Singh et al., “Human Dominant Disease Genes are Enriched in Paralogs Originating from Whole Genome Duplication,” by the authors of the original research article “Human Monogenic Disease Genes Have Frequently Functionally Redundant Paralogs.”

Network-based biomarkers for complex diseases.
Zhao XM, Chen L.
Journal of Theoretical Biology (2014)

In this special issue, we report the recent progress on computational approaches that are developed to identify biomarkers for complex diseases based on biological networks.

Pattern recognition in bioinformatics
Zhao XM, Ngom A, Hao JK.
Neurocomputing (2014)

Pattern recognition has been proven useful for handling and interpreting the accumulating large amount of biological data, and is widely used in bioinformatics.

A survey on computational approaches to identifying disease biomarkers based on molecular networks.
Qin G, Zhao XM.
Journal of theoretical biology (2014)

In this paper, we surveyed the recent progress on the computational approaches that have been developed to identify disease biomarkers based on molecular networks.